Pesquisa sobre: PHOSPHODIESTERASE I 
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Descritor Inglês:   Phosphodiesterase I 
Descritor Espanhol:   Fosfodiesterasa I 
Descritor Português:   Fosfodiesterase I 
Categoria:   D08.811.277.352.640.430
Definição Inglês:   A phosphoric diester hydrolase that removes 5'-nucleotides from the 3'-hydroxy termini of 3'-hydroxy-terminated OLIGONUCLEOTIDES. It has low activity towards POLYNUCLEOTIDES and the presence of 3'-phosphate terminus on the substrate may inhibit hydrolysis. 
Nota Histórica Inglês:   2004; use PHOSPHODIESTERASE I (NM) 1980-2003 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número do Registro:   38147 
Identificador Único:   D043264 

Ocorrência na BVS:
 

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